Monocytes Regulate T Cell Migration Through the Glia Limitans During Acute 1 Viral Encephalitis
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چکیده
Monocytes Regulate T Cell Migration Through the Glia Limitans During Acute 1 Viral Encephalitis 2 3 Carine Savarin 1 , Stephen A. Stohlman 1 , Roscoe Atkinson 2 , Richard M. Ransohoff 1 , and Cornelia C. 4 Bergmann 1 * 5 6 1 Department of Neurosciences NC30, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 7 Euclid Avenue, Cleveland, OH 44195, USA, 2 Department of Pathology, Keck School of Medicine, 8 University of Southern California, Los Angeles, California 90033, USA. 9 10 11 Running Title: Monocytes regulate migration across the glia limitans 12 13 Abstract: 213 words 14 Text: 5,223 words 15 16 17 *Corresponding author: 18 Cornelia C. Bergmann 19 Department of Neuroscience NC30 20 Lerner Research Institute 21 The Cleveland Clinic Foundation 22 9500 Euclid Avenue 23 Cleveland OH 44195 24 Phone (001) 216-444-5922 25 Fax (001) 216-444-7927 26 Email: [email protected] 27 Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Virol. doi:10.1128/JVI.00051-10 JVI Accepts, published online ahead of print on 3 March 2010
منابع مشابه
Monocytes regulate T cell migration through the glia limitans during acute viral encephalitis.
Leukocyte access into the central nervous system (CNS) parenchyma is tightly regulated by the blood-brain barrier (BBB). Leukocyte migration through the endothelial cell wall into the perivascular space is well characterized; however, mechanisms regulating their penetration through the glia limitans into the parenchyma are less well studied, and the role of monocytes relative to neutrophils is ...
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